Package: cohetsurr Type: Package Title: Assessing Complex Heterogeneity in Surrogacy Version: 2.0 Date: 2025-04-10 Authors@R: c(person("Rebecca", "Knowlton", email = "rknowlton@utexas.edu", role = c("aut")), person("Layla", "Parast", email = "parast@austin.utexas.edu", role = c("aut", "cre"))) Description: Provides functions to assess complex heterogeneity in the strength of a surrogate marker with respect to multiple baseline covariates, in either a randomized treatment setting or observational setting. For a randomized treatment setting, the functions assess and test for heterogeneity using both a parametric model and a semiparametric two-step model. More details for the randomized setting are available in: Knowlton, R., Tian, L., & Parast, L. (2025). "A General Framework to Assess Complex Heterogeneity in the Strength of a Surrogate Marker," Statistics in Medicine, 44(5), e70001 . For an observational setting, functions in this package assess complex heterogeneity in the strength of a surrogate marker using meta-learners, with options for different base learners. More details for the observational setting will be available in the future in: Knowlton, R., Parast, L. (2025) "Assessing Surrogate Heterogeneity in Real World Data Using Meta-Learners." A tutorial for this package can be found at . License: GPL Imports: stats, matrixStats, mvtnorm, mgcv, grf NeedsCompilation: no Packaged: 2026-07-09 08:51:47 UTC; root Author: Rebecca Knowlton [aut], Layla Parast [aut, cre] Maintainer: Layla Parast Config/pak/sysreqs: make Repository: https://laylaparast.r-universe.dev Date/Publication: 2025-04-11 02:10:02 UTC RemoteUrl: https://github.com/cran/cohetsurr RemoteRef: HEAD RemoteSha: bb573f94e6f4a07a7e2d90a9598f683867eea6ad